Description
What Is Butyrate?
Butyrate is a SCFA produced by healthy gut bacteria that break down dietary fiber. The primary source of butyrate is microbial fermentation in the colon. Consuming certain foods can help increase butyrate production. It is the primary energy course for colon cells, promoting their health and function. Butyrate also helps to maintain a healthy gut barrier, preventing and repairing leaky gut syndrome and repairs inflammation in the gut. Has been shown to help regulate blood sugar levels thereby improving insulin sensitivity and promotes weight loss by reducing appetite and increasing fat burning.
Role in Human Health
Butyrate plays a role in supporting gut health, including maintaining the intestinal lining, managing inflammation, supporting weight management, and metabolic health, and strengthening immune function. This SCFA is also a main energy source for colon cells, as it meets about 70% of this need.
Common Symptoms of Low Butyrate
Symptoms of low butyrate may include:
- Gastrointestinal issues (diverticulitis, Crohn’s disease, IBS, etc.): irregular bowel movements, bloating, diarrhea, acid reflux, gas, abdominal pain, and other digestive discomforts
- Systemic symptoms: frequent illnesses, unexplained inflammation, joint pain, and fatigue
- Insomnia: waking up tired, difficulty falling asleep, or problems staying asleep
- Inflammation: abdominal pain, fatigue, difficulty sleeping, joint pain, mood disorders, body weight fluctuations, and frequent infections and even helps to reduce acne flare ups.
- Insulin resistance
Individuals might also experience challenges with blood pressure management, allergies, arthritis pain, and other health concerns associated with lower butyrate levels.
Supplement with our Akkermansia probiotic (1 daily in AM) and a Butyrate supplement (2 daily in PM)
References:
PMID: 37523400 Tributyrin alleviates gut microbiota dysbiosis to repair intestinal damage
PMID: 32882837 Tributyrin Attenuates Metabolic and Inflammatory Changes Associated with Obesity through a GPR109A-Dependent Mechanism
PMID: 39870330 Oral tributyrin treatment affects short-chain fatty acid transport, mucosal health, and microbiome of inflammatory diarrhea
Prophylactic tributyrin treatment mitigates chronic-binge ethanol-induced intestinal barrier and liver injury PMID: 28087985
