Natural Metformin replacement. Berberine 500mg to support healthy blood sugar regulation. 60 capsules
(from Indian Barberry Berberis aristata root) dosage 1 each meal (total 3x daily)
Not all Berberine supplements are the same. You can be assured that our quality and form is the best.
Is this the answer to TYPE 2 DIABETES and INSULIN RESISTANCE? Suffering from any of the following?
1. Brain fogginess and inability to focus.
2. High blood sugar.
3. Intestinal bloating – most intestinal gas is produced from carbohydrates in the diet, mostly those that humans cannot digest and absorb.
4. Sleepiness, especially after meals.
5. Weight gain, fat storage, difficulty losing weight – for most people, excess weight is from high fat storage; the fat in IR is generally stored in and around abdominal organs in both males and females.
6. Increased blood triglyceride levels.
7. Increased blood pressure. Many people with hypertension are either diabetic or pre-diabetic and have elevated insulin levels due to insulin resistance. One of insulin’s effects is to control arterial wall tension throughout the body. 8. Increased pro-inflammatory cytokines associated with cardiovascular disease.
9. Depression. Due to the deranged metabolism resulting from insulin resistance, psychological effects, including depression, are not uncommon.
- Increased hunger.
- Acne (cystic)
- Imbalanced adrenal and ovarian hormones (estrogens, progesterone, cortisol, Dhea, Testosterone)
- Sugar and/or carb craving
- Waking in middle of night (between 2-4)
- Suffering from osteoarthritis
- Notice “skin tags” on body
Insulin resistance (IR) which is a physiological condition in which cells fail to respond to the normal actions of the hormone insulin. The body produces insulin, but the cells in the body become resistant to insulin and are unable to use it as effectively, leading to hyperglycemia.
Beta cells in the pancreas subsequently increase their production of insulin, further contributing to hyperinsulinemia. This often remains undetected and can contribute to a diagnosis of Type 2 Diabetes.
One of insulin’s functions is to regulate delivery of glucose into cells to provide them with energy. Insulin resistant cells cannot take in glucose, amino acids and fatty acids. Thus, glucose, fatty acids and amino acids ‘leak’ out of the cells. A decrease in insulin/glucagon ratio inhibits glycolysis which in turn decreases energy production. The resulting increase in blood glucose may raise levels outside the normal range and cause adverse health effects, depending on dietary conditions. Certain cell types such as fat and muscle cells require insulin to absorb glucose. When these cells fail to respond adequately to circulating insulin, blood glucose levels rise. The liver helps regulate glucose levels by reducing its secretion of glucose in the presence of insulin. This normal reduction in the liver’s glucose production may not occur in people with insulin resistance.
Insulin resistance in muscle and fat cells reduces glucose uptake (and also local storage of glucose as glycogen and triglycerides, respectively), whereas insulin resistance in liver cells results in reduced glycogen synthesis and storage and also a failure to suppress glucose production and release into the blood. Insulin resistance normally refers to reduced glucose-lowering effects of insulin. However, other functions of insulin can also be affected. For example, insulin resistance in fat cells reduces the normal effects of insulin on lipids and results in reduced uptake of circulating lipids and increased hydrolysis of stored triglycerides.
Increased mobilization of stored lipids in these cells elevates free fatty acids in the blood plasma. Elevated blood fatty- acid concentrations (associated with insulin resistance and diabetes mellitus Type 2), reduced muscle glucose uptake, and increased liver glucose production all contribute to elevated blood glucose levels.
High plasma levels of insulin and glucose due to insulin resistance are a major component of the metabolic syndrome. If insulin resistance exists, more insulin needs to be secreted by the pancreas. If this compensatory increase does not occur, blood glucose concentrations increase and type 2 diabetes occurs.
Because insulin is one of the “major” hormones, it’s also impossible for your body to balance its minor” hormones (estrogen, progesterone and testosterone among them) until your insulin metabolism is balanced first. To put it simply, if you have hot flashes and you are insulin resistant, it’s going to be nearly impossible to cure the hot flashes without first healing the insulin resistance. As women approach menopause, they become increasingly intolerant of carbohydrates and find it easier to gain weight, especially around their waists. Afternoon blahs, sugar crashes and carbohydrate cravings may all be early insulin resistance symptoms.
When the cells won’t absorb the extra glucose, the liver has to convert it into fat. Fat cells are loaded with glucose receptors, so this is a vicious cycle. Ironically, while the insulin-resistant woman is gaining weight, her cells are actually “starved” for glucose, so she feels exhausted and tends to eat carbohydrate-heavy foods in search of energy.
These extra fat cells are also little estrogen factories. So weight gain contributes to the estrogen dominance that causes so many symptoms during the early stages of perimenopause.
Symptoms relating to syndrome X usually predate the onset of menopause, but most women do not complain of them until then. A woman’s health can deteriorate rapidly during menopause with the decrease of estrogen levels in the body. And digestive issues that were once merely a hassle become an affliction when the body’s natural defenses against inflammation (estrogen being one) are depleted.
Women approaching menopause are particularly prone to becoming insulin resistant due to metabolic changes related to fluctuations in adrenal and thyroid secretions. In fact, the decrease of certain hormones, like estradiol, may trigger a resistance to insulin in patients who never experienced it before. Certain blood pressure medications can mask symptoms without treating the problem. Frequently, women unwittingly make their symptoms worse by trying to lose weight with low-fat, high-carbohydrate diets.
Your body’s hormonal balance is like a symphony. Insulin is one of the loudest and most important instruments. When its metabolism goes wrong, it throws off everything else. We’ve seen over and over how women with menopause symptoms must reverse their insulin resistance in order to find relief from other symptoms. It can be done, and we’re here to help.
Enter BERBERINE (our MODULATOR supplement)… In numerous clinical studies it was found that berberine is a potent oral agent with modest effect on lipid metabolism. It is safe and the cost of treatment by berberine is very low. It may serve as a new drug candidate in the treatment of type 2 diabetes. And was found to be at least as potent in reducing high glucose and insulin levels as the METFORMIN drug without all the side effects!
Berberine is a phytochemical (plant chemical) found in many different plants. When used in herbal medicine, the usual sources are barberry, goldenseal, or Oregon grape. It’s the main alkaloid of Coptis chinensis, which Asian folk medicine uses to treat diabetes. You also may hear people refer to Coptis chinensis as Chinese Goldthread, Huang-Lian, and Huang- LienIt.
Berberine has a lot of uses. It can treat heart disease, immune disorders, digestive problems, eye infections, and other infections.
One study, published just last year looked at the effect of berberine on how well muscle cells take in sugar. As you probably already know, except when we are actively exercising, sugar cannot get into muscle cells unless insulin is present to escort it in. That’s why the blood sugar goes up when patients either don’t have enough insulin, or when the insulin they do have doesn’t work effectively, a condition called insulin resistance.
In the study, the researchers exposed muscle cells from rats to berberine, and then examined what happened. What they discovered was amazing.
The berberine solution had the same effect on the cells as insulin.
Just like insulin, it activated the same biochemical pathway (protein kinase phosphorylation activation of GLUT-4) that signals cells to take up more sugar. And just like insulin, the greater the amount of berberine they exposed the cells to, the more sugar they took up. All this happened in the absence of any insulin!
There is one small problem with measuring blood insulin levels – they are not always accurate. Even if your levels look adequate, they may not be. That’s why you may not respond fully to normal “medical treatment” for diabetes. You need an insulin-like effect in order to achieve complete control of your sugar levels. And this study shows that this is exactly what berberine has to offer.
Many clients who are taking insulin or drugs designed to increase insulin may be able to either stop them or reduce them after starting berberine. This of course would have to be tightly monitored.
Better than metformin for diabetes
Now I’d like to tell you about another study that proves this. In fact, this study shows that berberine might just be the best medication there is, natural or otherwise, for diabetes.
This study looked at the effect of berberine on 36 patients. All of them were newly diagnosed cases of type-2 diabetes.
Half of the patients took 500 mg, three times daily of the drug metformin (also known as Glucophage). The other half took berberine (berberine hydrochloride) in the same dose – 500 mg, three times a day. Then the researchers measured the participants’ blood sugar levels for the next three months. Here’s what happened: In terms of blood sugar control, both treatments worked equally as well. The fasting blood sugars went down 30%. And the sugar levels after eating (called the post prandial levels) went down even more – 45%.
But here’s the really astounding thing about berberine. All of this happened within the first two to four weeks of taking the treatment. And unlike metformin, there were no side effects at all in any of the patients taking berberine. In addition to the sugar levels, the A1c levels went down as well – a full 20%. That may not sound like a lot. But it’s a very significant improvement.
Triglycerides are the fats found in the bloodstream that the cells metabolize for energy. Since type-2 diabetics do not effectively burn fat (that’s why they get fat), their triglyceride levels are always elevated.
In this study, those patients taking berberine had a reduction in their triglyceride levels of 21%. Those taking metformin had no reduction at all. This indicates that berberine not only improves sugar metabolism, it also improves fat metabolism. This might make berberine the most effective overall medication for diabetes that exists today, including pharmaceuticals. In fact, the authors of the study stated that berberine “can serve as a new class of anti-diabetic medication.”
What Conditions Is Berberine Good For?
• Diabetes / and Inulin resistance
• Heart disease
• High cholesterol
• Hypertension (high blood pressure) • Immune challenges
• Intestinal infections
• Joint problems
• Low bone density
• Weight control
• Fighting cancer
• Guarding against Alzheimer’s
• Natural antibiotic. The list of micro-organisms berberine works against is a long one, including staphylococcus,
streptococcus, chlamydia, diphtheria, salmonella, vibrio cholera, diplococcus pneumonia, pseudomonas, gonorrhea, candida (technically a fungus). It also has shown to work again the following parasites: Giardia lamblia, Trichomonas vaginalis, Entamoeba histolytic and Leishmania donovani. In one study comparing the effects of berberine to the patent medicine, Metronidazole (Flagyl) just half a dose of berberine was nearly as effective against parasites as Metronidzole at full dose!
It’s showing great promise against MRSA (methicillin-resistant staphylococcus aureus) or “flesh eating bacteria.
Another study found berberine has the ability to kill the germ “helicobacter pylori” and at low doses of berberine it can inhibit H-Pylori from even growing!
Amazingly this little powerhouse herb does NOT kill the good bacteria in your gut!
Legal: The information provided is not intended as a means of diagnosis or treating illness or as a replacement for any medicine or advice from a competent physician. Individuals having serious health problems should consult a competent licensed physician specializing in their condition. These statements have not been evaluated by the FDA. We assume no responsibility for anyone choosing to self-administer any suggestions in this publication; they do so on their own determinism. The information in this publication is for educational purposes only.